The US Food and Drug Administration (FDA) issued a draft guidance on Friday to assist sponsors in using Bayesian methods to support the safety and effectiveness of new drugs in clinical trials. These ...

Bayesian methods offer a coherent framework for evaluating diagnostic tests by combining prior knowledge with observed data to yield posterior estimates of test accuracy and disease prevalence. At the ...

The FDA's move to incorporate Bayesian statistical methods into clinical trials of drugs and biologics garnered special treatment in JAMA this week. JAMA published three perspectives -- two welcoming ...

This course provides a rigorous yet practical introduction to Bayesian methods for statistical inference, probabilistic modeling, knowledge representation, and decision-making under uncertainty.

The European Medicines Agency (EMA) has begun a consultation into the use of Bayesian methods in the analysis of clinical trial data. Bayesian methods are one of the main approaches to statistical ...

The FDA’s new draft guidance on Bayesian methods in clinical trials has been hailed by some as a breakthrough that could speed drug development. But statisticians and researchers are divided on ...

Childhood Cancer Data Initiative Participant Index: Mapping Pediatric Cancer Data to Facilitate Cross-Study Integrated Analysis Using published summary data from JAVELIN Renal 101, we modeled PFS on ...

Approaches for statistical inference -- The Bayes approach -- Bayesian computation -- Model criticism and selection -- The empirical Bayes approach -- Bayesian design -- Special methods and models -- ...

Marty Makary was appointed commissioner of the Food and Drug Administration (FDA) in 2025. The prominent surgeon, medical researcher, bestselling author, and critic of the medical ...