Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren’t ...

Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA—its genome—and segregate it equally ...

Scientists have identified key changes to both chromosome structure and gene expression that affect stem cell function during aging. Using fruit flies, they found that these changes led to stem cell ...

Aging men often lose the Y chromosome in a growing number of their cells—and it may be far more dangerous than once believed.

Chromosomal rearrangements, such as chromosome segment inversions, may affect the epigenetic landscape as well as gene expression. Indeed, different kinds of chromosome segment inversions have been ...

One of the challenges of working with ancient DNA samples is that damage accumulates over time, breaking up the structure of the double helix into ever smaller fragments. In the samples we’ve worked ...

The centromere is necessary for the transport of chromosomes during cell division and, therefore, for the correct transmission of genetic information. Most plants and animals have chromosomes with a ...

Chromosomal rearrangements, such as chromosome segment inversions, may affect the epigenetic landscape as well as gene expression. Different kinds of chromosome segment inversions have been found in ...