The complement system is an intricate network of plasma proteins that defends against pathogens and clears cellular debris. Under normal conditions, activation proceeds through classical, lectin and ...

The complement system, a key component of innate immunity, exerts profound influence on the initiation, progression and destabilisation of atherosclerotic plaques. Activation may proceed via the ...

Among people with sickle cell disease—an inherited blood disorder—acute chest syndrome (ACS) is the leading cause of death. The condition is the result of red blood cells becoming stiff, sticky, and ...

And this first part is going to focus on the mouse model and the translational research that kind of started giving us a pretty major clue of how the complements involve, what pathways involve, and ...