Tousled-like kinases (TLKs) are conserved serine/threonine kinases that orchestrate chromatin dynamics during DNA replication and repair. These enzymes transiently associate with histone chaperones ...

DNA polymerase delta (Pol δ) is a central enzyme in eukaryotic genome duplication and maintenance, operating as a four-subunit holoenzyme composed of one catalytic subunit (POLD1) and three accessory ...

A newly mapped step in DNA replication suggests that strand separation begins at a precise junction between two helicase ...

(Alones Creative/iStock/Getty Images) One of the most iconic visual representations in biological science is the double helix ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...

Researchers at the University of Minnesota Medical School have developed a new method called PARTAGE that provides a clearer picture of how the genome is regulated and disrupted in diseases like ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified in a new study. In a new paper published in Nature Communications, an ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind DNA ...

If parent cells and their daughter cells are to share a stable identity, parent cells must divide—and replicate their DNA—while ensuring that their histones are distributed properly to their daughter ...

A blue-and-gray 3D representation of a strand of DNA with other strands floating in the background. Google has officially released its AlphaGenome machine learning model, which can predict the ...