Scientists have discovered that a protein once thought to simply help load a factor necessary for the copying of DNA, actually plays a key role in ensuring fast and reliable replication—an insight ...

PHILADELPHIA – When cells in the human body divide, they must first make accurate copies of their DNA. The DNA replication exercise is one of the most important processes in all living organisms and ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular aging, cancer, ...

Researchers have gained a clearer insight into how common alterations to the structure of DNA affect the process of DNA replication. These structural changes can put a stop to replication, causing ...

In a twist on the question, 'Which came first, the chicken or the egg?', scientists have long faced a similar question about how human adenovirus replicates: 'Which comes first, assembly of the viral ...

Every day, billions of cells in your body divide, helping to replace old and injured cells with new ones. And each time this happens, your entire genetic library—your genome, which totals more than 3 ...

An elegant collaboration between researchers in the UK's two core-funded Medical Research Council Research Institutes, the Laboratory of Medical Sciences (LMS) in London and the Laboratory of ...

If the engines of DNA replication stay in high gear all the time, they eventually stall or even break down. Fortunately, these engines, which consist of protein complexes, have what could be called ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

The researchers suspect that 55LCC may be involved in regulating not just the DNA replication process associated with cell division, but also when DNA damaging lesions block replication. Discover the ...