The authors discuss the theory of ion mobility spectrometry, its benefit over HPLC analysis in cleaning verification, and the experimental considerations for method validation and validation. The ...

Chromatography is the science of separating molecules of interest to identify, quantify or even purify them. Properties of the target molecules such as their solubility, size or hydrophobicity give ...

Ion exchange separates components in a sample depending on their relative ionic strengths and interaction with the stationary phase. The stationary phase is a charged substance that selectively ...

The most widely utilized technique for total GOS determination is based on enzymatic hydrolysis to break down the complex molecules into simple carbohydrates before their chromatographic analysis.

This article presents a simple and systematic approach to HPLC method development, beginning with sample preparation and finishing with practical analytical method validation. step 5 - method ...