(SALT LAKE CITY)—A new study by researchers at the University of Utah School of Medicine sheds light on a longstanding question about the role of mitochondria in debilitating and fatal motor neuron ...
A new study reveals that astrocytes—star-shaped support cells traditionally viewed as passive partners of neurons—play a previously underappreciated role in the maturation of coordinated movement. A ...
Apitegromab improved motor function in SMA patients in a Phase 3 trial analysis, with stronger benefits seen in those treated earlier.
Scientists have traced connectivity between neurons to identify how the brain communicates with the spinal cord. A new brain map visualizes the connections between the brain and spinal cord at the ...
Some patients with later-onset spinal muscular atrophy (SMA) type 2 and type 3 had improved motor function when the investigational monoclonal antibody apitegromab was added to their treatment, the ...
Motor neurons are some of the largest cells in the human body. In particular, upper neurons—extending from the cerebral cortex to the brain stem or spinal cord—average 60μm in diameter. 3,4 These ...
A new McGill University study has found a direct link between age-related declines in neuron activity in the cerebellum and ...
A new drug-free, minimally invasive intervention targets the root cause of progressive loss of neural function in spinal muscle atrophy (SMA), an inherited neuromuscular disease. An intervention, ...
By examining mice across the lifespan, researchers showed that age lowers firing rates in cerebellar Purkinje cells, leading to poorer motor coordination. Reversing this decline improved performance, ...
Researchers have uncovered in anglerfish a specialized motor neuron population for the first dorsal fin used for 'fishing'. When the first dorsal fin evolved from a swimming and buoyancy aid to a ...
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