Optimizing microbial growth media is vital for industrial bioprocessing, yet traditional Design of Experiments often struggles with complex component interactions. This study evaluates Batch Bayesian ...
RT01: A first-in-class theranostic radionuclide drug conjugate (RDC) with zirconium-89 and lutetium-177 targeting tissue factor. Debio 0123 (zedoresertib), a selective WEE1 inhibitor, in combination ...
ABSTRACT: This study develops a stochastic and behavioral extension of a Pyomo-based mixed-integer linear programming (MILP) framework to optimize dynamic electricity tariffs in Senegal under ...
In this tutorial, we implement an advanced Bayesian hyperparameter optimization workflow using Hyperopt and the Tree-structured Parzen Estimator (TPE) algorithm. We construct a conditional search ...
Cancer Res (2026) 86 (7_Supplement): 6435. Project Optimus encourages early identification of the Optimal Biological Dose (OBD) by balancing efficacy and safety, moving beyond the maximum tolerated ...
Abstract: Accurate valuation of agency mortgage-backed securities (MBS) is crucial for their risk management and market pricing, and the core challenge lies in the efficient and accurate calibration ...
Abstract: We propose a guided multi-fidelity Bayesian optimization framework for data-efficient controller tuning that integrates corrected digital twin simulations with real-world measurements. The ...
pyBO is a Python library for Bayesian Optimization of single and multi objective problems. Built on top of BoTorch and using Gaussian Processes as surrogate models, it provides a user-friendly ...